Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 6/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950838 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL2557217 | 0.81 | HSD17B10 (0.74) | ALDH1A1SMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL7390502 | 0.80 | ACACB (0.51) | ALDH1A1HPGD | |
| SCHEMBL29952903 | 0.79 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL2553344 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL6538870 | 0.79 | RAB9A (0.63) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL29954636 | 0.78 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL29953203 | 0.78 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL29952142 | 0.77 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2559279 | 0.77 | FAAH (0.52) | ALDH1A1SMN1; SMN2LMNAFAAHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |