Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ATF4 | P18848 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952142 | 0.94 | ALDH1A1 (0.81) | ALDH1A1LMNAATF4HTTSMN1; SMN2 | |
| SCHEMBL29955306 | 0.93 | ALDH1A1 (0.83) | ALDH1A1LMNAATF4HTTSMN1; SMN2 | |
| SCHEMBL29956853 | 0.93 | ALDH1A1 (0.83) | ALDH1A1LMNAATF4HTTSMN1; SMN2 | |
| SCHEMBL2556699 | 0.90 | ALDH1A1 (0.64) | ALDH1A1LMNAATF4HTTHPGD | |
| SCHEMBL29954343 | 0.85 | MAPT (0.61) | ALDH1A1LMNAATF4RAB9AKMT2A | |
| SCHEMBL29956675 | 0.83 | HPGD (0.61) | ALDH1A1LMNAATF4HTTHPGD | |
| SCHEMBL17658518 | 0.81 | LMNA (0.72) | ALDH1A1LMNAATF4HTTHPGD | |
| SCHEMBL17658509 | 0.81 | LMNA (0.72) | ALDH1A1LMNAATF4HTTHPGD | |
| SCHEMBL16083047 | 0.81 | ATF4 (1.00) | ALDH1A1LMNAATF4HTTHPGD | |
| SCHEMBL12629118 | 0.81 | LMNA (0.72) | ALDH1A1LMNAATF4HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |