Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.64 |
| ▸ | ERN1 | O75460 | 5/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.53 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527079 | 1.00 | GABRA1 (0.64) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL7095671 | 0.91 | GABRA1 (0.53) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL29953931 | 0.86 | ERN1 (0.52) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL1527632 | 0.86 | ERN1 (0.52) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL8444934 | 0.85 | ERN1 (0.59) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL21002293 | 0.85 | ERN1 (0.59) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL8431195 | 0.85 | ERN1 (0.50) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL8406803 | 0.83 | ERN1 (0.48) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL193427 | 0.83 | ALOX5 (0.49) | GABRA1GABRB2ERN1TLR2TLR1 | |
| SCHEMBL30225047 | 0.83 | ERN1 (0.57) | GABRA1GABRB2ERN1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3994142-A1 | CHEMICAL COMPOUNDS | Borah, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |