Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15333187 | 0.85 | MAPT (0.47) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29952044 | 0.85 | MAPT (0.49) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2552009 | 0.83 | MAPT (0.43) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29953116 | 0.82 | KDM4E (0.37) | MAPTMEN1KMT2ANPC1PIK3CD | |
| SCHEMBL29957073 | 0.81 | SMN1; SMN2 (0.50) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29953250 | 0.81 | MMP2 (0.46) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2561352 | 0.80 | ALOX5 (0.38) | PGR | |
| SCHEMBL29951558 | 0.80 | TNKS2 (0.43) | MAPTLMNAALDH1A1 | |
| SCHEMBL15331543 | 0.77 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL15332461 | 0.76 | MAPT (0.45) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |