Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331543 | 0.89 | MAPT (0.42) | SMN1; SMN2MAPTALDH1A1TDP1THRB | |
| SCHEMBL15333187 | 0.88 | MAPT (0.47) | MAPTALDH1A1TDP1THRBMMP2 | |
| SCHEMBL29955457 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALDH1A1TDP1MMP2 | |
| SCHEMBL15329681 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1TDP1THRB | |
| SCHEMBL29955733 | 0.84 | ABCB1 (0.40) | SMN1; SMN2MAPTALDH1A1TDP1NPC1 | |
| SCHEMBL2552009 | 0.84 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1TDP1THRB | |
| SCHEMBL15330037 | 0.82 | MMP2 (0.50) | MAPTALDH1A1TDP1THRBMMP2 | |
| SCHEMBL15332084 | 0.82 | CNR1 (0.40) | SMN1; SMN2MAPTALDH1A1TDP1THRB | |
| SCHEMBL29953250 | 0.81 | MMP2 (0.46) | SMN1; SMN2MAPTALDH1A1TDP1THRB | |
| SCHEMBL29953933 | 0.81 | MAPT (0.48) | SMN1; SMN2MAPTALDH1A1TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |