Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204987 | 0.82 | MEN1 (0.40) | HDAC4HDAC1MEN1NPC1GAA | |
| SCHEMBL15627435 | 0.82 | LCK (0.48) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL3784350 | 0.82 | BRD9 (0.42) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL31307595 | 0.82 | HNF4A (0.46) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL3780741 | 0.80 | RXFP1 (0.43) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL1006953 | 0.79 | NLRP3 (0.43) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL29956316 | 0.79 | NLRP3 (0.43) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL29246623 | 0.78 | RXFP1 (0.38) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL1677060 | 0.78 | ENPP2 (0.45) | GAAATRCA12CA1CA7 | |
| SCHEMBL28444082 | 0.77 | CHRM3 (0.52) | MEN1KMT2ABRD9CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |