Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formylchromone SCHEMBL30783534 | 0.88 | PTPN1 (1.00) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL127924 | 0.79 | PTPN1 (1.00) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL29952282 | 0.79 | PTPN1 (1.00) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL28990301 | 0.78 | PTPN1 (0.64) | PTPN1PTPN2MAOBPOLBKDM4E | |
| SCHEMBL7025708 | 0.77 | PTPN1 (0.86) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL23707495 | 0.76 | PTPN1 (0.67) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL13978663 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL911098 | 0.76 | ALDH1A1 (0.68) | PTPN1PTPN2MAOBMAOAMEN1 | |
| SCHEMBL5363245 | 0.76 | PTPN1 (1.00) | PTPN1PTPN2MAOBMAOAPOLB | |
| SCHEMBL12174817 | 0.76 | PTPN1 (0.67) | PTPN1PTPN2MAOBMAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |