Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956720 | 0.80 | KIF11 (0.50) | KIF11HPGDHTR1DHTR1BMEN1 | |
| SCHEMBL29951414 | 0.79 | MEN1 (0.44) | KDM4EGAAKIF11HPGDHTT | |
| SCHEMBL29951788 | 0.79 | HPGD (0.44) | HPGDMAPTALDH1A1LMNA | |
| SCHEMBL10067359 | 0.78 | KDM4E (0.44) | KDM4EGAAKIF11HTR1DMAPT | |
| SCHEMBL1429232 | 0.77 | ALDH1A1 (0.53) | KDM4EGAAHPGDMAPTALDH1A1 | |
| SCHEMBL29954927 | 0.77 | KIF11 (0.40) | KDM4EKIF11HPGDHTR1DMAPT | |
| SCHEMBL3921504 | 0.75 | KIF11 (0.53) | KDM4EKIF11HPGDMAPTALDH1A1 | |
| SCHEMBL29956620 | 0.75 | L3MBTL1 (0.58) | HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL29951382 | 0.75 | HPGD (0.43) | KIF11HPGDPTPN1 | |
| SCHEMBL29952372 | 0.74 | HPGD (0.64) | GAAKIF11HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |