Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952046 | 0.82 | JAK2 (0.37) | LMNAALDH1A1MAPK1MAPTPTGDR2 | |
| SCHEMBL29951670 | 0.79 | MEN1 (0.40) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29955172 | 0.77 | TDP1 (0.41) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7371438 | 0.76 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL2557425 | 0.75 | MEN1 (0.40) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14398071 | 0.75 | KDM4E (0.44) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29952124 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL29952265 | 0.73 | ALDH1A1 (0.37) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29955001 | 0.73 | S1PR1 (0.39) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL29952749 | 0.73 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |