Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952749 | 0.85 | ALDH1A1 (0.37) | ALDH1A1ALDH1A3TRPM8LMNAMAPK1 | |
| SCHEMBL29952124 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3TRPM8MEN1KMT2A | |
| SCHEMBL29953969 | 0.79 | ALDH1A3 (0.43) | ALDH1A1ALDH1A3ALDH3A1HPGD | |
| SCHEMBL2562764 | 0.79 | ALDH1A1 (0.40) | ALDH1A1ALDH1A3ALDH3A1HPGD | |
| SCHEMBL29955001 | 0.77 | S1PR1 (0.39) | ALDH1A1TRPM8MEN1KMT2ALMNA | |
| SCHEMBL29952046 | 0.75 | JAK2 (0.37) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL2560571 | 0.75 | ALDH1A1 (0.37) | ALDH1A1ALDH1A3ALDH3A1HPGD | |
| SCHEMBL2555361 | 0.74 | ALDH1A3 (0.38) | ALDH1A1ALDH1A3MEN1KMT2ANPSR1 | |
| SCHEMBL29954068 | 0.73 | LMNA (0.38) | ALDH1A1TRPM8MEN1KMT2ALMNA | |
| SCHEMBL29952977 | 0.72 | ALDH1A1 (0.44) | ALDH1A1ALDH1A3TRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |