Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952265 | 0.85 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPK1ALDH1A3TRPM8 | |
| SCHEMBL29952046 | 0.81 | JAK2 (0.37) | ALDH1A1LMNAMAPK1MAPTJAK2 | |
| SCHEMBL29952786 | 0.79 | ALDH1A3 (0.40) | ALDH1A1SMN1; SMN2PARP10PLA2G7ALDH1A3 | |
| SCHEMBL29952124 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPK1PARP10ALDH1A3 | |
| SCHEMBL2554161 | 0.77 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2PLA2G7ALDH1A3TSHR | |
| SCHEMBL2561620 | 0.74 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2PLA2G7ALDH1A3TSHR | |
| SCHEMBL29954068 | 0.73 | LMNA (0.38) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL2558260 | 0.73 | ALDH1A3 (0.38) | ALDH1A1SMN1; SMN2MAPTALDH1A3TSHR | |
| SCHEMBL29955126 | 0.71 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ALDH1A3 | |
| SCHEMBL29951670 | 0.69 | MEN1 (0.40) | ALDH1A1LMNAMAPK1TSHRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |