Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951041 | 0.79 | KMT2A (0.48) | MEN1KMT2AALDH1A1TDP1MAPK1 | |
| SCHEMBL29954068 | 0.79 | LMNA (0.38) | MEN1KMT2AALDH1A1TDP1MAPK1 | |
| SCHEMBL29955447 | 0.77 | KMT2A (0.46) | MEN1KMT2AALDH1A1TDP1TSHR | |
| SCHEMBL29952257 | 0.74 | KMT2A (0.42) | MEN1KMT2AALDH1A1TDP1TSHR | |
| SCHEMBL2559520 | 0.72 | RORC (0.41) | MEN1KMT2AALDH1A1TDP1TSHR | |
| SCHEMBL29957441 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1TDP1TSHR | |
| SCHEMBL29952046 | 0.70 | JAK2 (0.37) | ALDH1A1MAPK1SLC6A9SLC6A5LMNA | |
| SCHEMBL29952124 | 0.70 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPK1HPGD | |
| SCHEMBL29952749 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MAPK1TSHRLMNATRPM8 | |
| SCHEMBL29952265 | 0.69 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |