Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558251 | 0.88 | LIPE (0.56) | LIPESMN1; SMN2LMNAALDH1A1ENPP2 | |
| SCHEMBL2553447 | 0.86 | CYP11B1 (0.52) | — | |
| SCHEMBL1956146 | 0.85 | LIPE (0.71) | LIPELMNAENPP2FFAR1FFAR4 | |
| SCHEMBL29825616 | 0.85 | LIPE (0.71) | LIPELMNAENPP2FFAR1FFAR4 | |
| SCHEMBL29957888 | 0.84 | LIPE (0.47) | LIPELMNAALDH1A1ENPP2ABCB1 | |
| SCHEMBL2561025 | 0.84 | LIPE (0.51) | LIPECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29953323 | 0.83 | LRRK2 (0.50) | LIPELMNAALDH1A1ENPP2LRRK2 | |
| SCHEMBL2557388 | 0.82 | CCR5 (0.55) | LIPESMN1; SMN2ALDH1A1ENPP2FFAR1 | |
| SCHEMBL13723490 | 0.82 | ENPP2 (0.58) | LIPECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29958205 | 0.81 | LIPE (0.75) | LIPESMN1; SMN2LMNAALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |