Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KLK8 | O60259 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | KLK14 | Q9P0G3 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957121 | 0.85 | LRRK2 (0.51) | LRRK2LIPEHTR1ADRD2ENPP2 | |
| SCHEMBL29957711 | 0.85 | LIPE (0.69) | SGMS2LIPEHTR1ADRD2ENPP2 | |
| SCHEMBL29954070 | 0.83 | LIPE (0.50) | LRRK2LIPEENPP2ALDH1A1LMNA | |
| SCHEMBL29825616 | 0.83 | LIPE (0.71) | LRRK2LIPEENPP2LMNA | |
| SCHEMBL1956146 | 0.83 | LIPE (0.71) | LRRK2LIPEENPP2LMNA | |
| SCHEMBL13723490 | 0.83 | ENPP2 (0.58) | LIPEENPP2HTR6LMNAKMT2A | |
| SCHEMBL2558251 | 0.80 | LIPE (0.56) | LRRK2LIPEHTR1AENPP2ALDH1A1 | |
| SCHEMBL2038362 | 0.80 | HTR1A (0.51) | LRRK2SGMS2HTR1ADRD2CYP11B1 | |
| SCHEMBL29955603 | 0.79 | LIPE (0.44) | SGMS2LIPEENPP2LMNAKMT2A | |
| SCHEMBL16498115 | 0.78 | LRRK2 (0.67) | LRRK2SGMS2HTR1ADRD2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |