Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327084 | 0.78 | HRH3 (0.41) | HRH3KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL19243066 | 0.78 | HPGD (0.40) | HRH3ALDH1A1MAPTKMT2A | |
| SCHEMBL2776485 | 0.73 | SELL (0.46) | HRH3KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL29954178 | 0.73 | LPL (0.43) | LPLLIPGCA2 | |
| SCHEMBL30979268 | 0.73 | SELL (0.46) | HRH3KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL31366444 | 0.72 | ACHE (0.38) | KDM4EALDH1A1LPLLIPGLMNA | |
| SCHEMBL7232450 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1LPLLIPGLMNA | |
| SCHEMBL7776329 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1LPLLIPGLMNA | |
| SCHEMBL30274968 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1LPLLIPGLMNA | |
| SCHEMBL18966864 | 0.70 | KMT2A (0.40) | HRH3KDM4EALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |