Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253115 | 1.00 | TRIM24 (0.52) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL16570096 | 0.80 | TRIM24 (0.44) | TRIM24TRIM33KMT2AMEN1KDM4E | |
| SCHEMBL20153719 | 0.80 | KDM4E (0.37) | TRIM24TRIM33LMNAALDH1A1KDM4E | |
| SCHEMBL18726709 | 0.80 | KDM4E (0.37) | TRIM24TRIM33LMNAALDH1A1KDM4E | |
| SCHEMBL2062668 | 0.77 | KCNA5 (0.51) | TRIM24TRIM33KMT2AMEN1ERN1 | |
| SCHEMBL9000291 | 0.76 | KDM4E (0.38) | TRIM24TRIM33LMNAALDH1A1KDM4E | |
| SCHEMBL6493230 | 0.74 | GRM5 (0.50) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2215225 | 0.74 | TRIM24 (0.42) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL20797705 | 0.74 | TRIM24 (0.42) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL832535 | 0.74 | TRIM24 (0.42) | TRIM24TRIM33KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333819-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | Katholieke Universiteit Leuven (BE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022233877-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-11-10 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |