Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000291 | 0.81 | KDM4E (0.38) | KDM4EAPPSNCAALDH1A1 | |
| SCHEMBL4160827 | 0.77 | NFE2L2 (0.47) | KDM4ENFE2L2TRPA1CYP11B1CYP11B2 | |
| SCHEMBL29094920 | 0.77 | KDM4E (0.49) | GRM5KDM4ENFE2L2TRPA1CYP11B1 | |
| SCHEMBL4160819 | 0.77 | NFE2L2 (0.47) | KDM4ENFE2L2TRPA1CYP11B1CYP11B2 | |
| SCHEMBL9166069 | 0.76 | KDM4E (0.51) | KDM4ENFE2L2TRPA1CYP11B1CYP11B2 | |
| SCHEMBL29954331 | 0.74 | TRIM24 (0.52) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL12253115 | 0.74 | TRIM24 (0.52) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL18726709 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL20153719 | 0.74 | KDM4E (0.37) | KDM4EAPPSNCAALDH1A1 | |
| SCHEMBL3397695 | 0.74 | FGF23 (0.51) | KDM4ENFE2L2TRPA1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | BF RESEARCH INSTITUTE (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | PRNP, PRPH, PCNP | GRM5 3408/4885RELA 3311/4885KDM4E 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.