Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951681 | 0.88 | ALDH1A1 (0.77) | ALDH1A1PTGDR2MEN1KMT2APOLB | |
| SCHEMBL2558934 | 0.87 | ALDH1A1 (0.80) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL5883468 | 0.86 | L3MBTL1 (0.56) | ALDH1A1L3MBTL1GLALMNAPTGDR2 | |
| SCHEMBL16832271 | 0.84 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1LMNAPTGDR2KMT2A | |
| SCHEMBL29955281 | 0.82 | LMNA (0.77) | ALDH1A1L3MBTL1GLALMNAPTGDR2 | |
| SCHEMBL1787396 | 0.81 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1LMNAPOLBMAPT | |
| SCHEMBL6818074 | 0.78 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL5882317 | 0.78 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1GLALMNAPTGDR2 | |
| SCHEMBL2559619 | 0.75 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL7390751 | 0.75 | ALDH1A1 (0.76) | ALDH1A1L3MBTL1GLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |