Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TACR2 | P21452 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | DVL1 | O14640 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14787928 | 0.92 | ALDH1A1 (0.63) | ALDH1A1KDM4EL3MBTL1GLAPOLB | |
| SCHEMBL493684 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KDM4EL3MBTL1TACR2MAPT | |
| SCHEMBL30159697 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KDM4EL3MBTL1TACR2MAPT | |
| SCHEMBL2560646 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KDM4EL3MBTL1TACR2POLB | |
| SCHEMBL13858849 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1TACR2POLB | |
| SCHEMBL6536289 | 0.86 | POLB (0.74) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL5246469 | 0.86 | POLB (0.65) | ALDH1A1KDM4EPOLBMAPTHTT | |
| SCHEMBL29956334 | 0.86 | POLB (0.65) | ALDH1A1KDM4EPOLBMAPTHTT | |
| SCHEMBL2561054 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EL3MBTL1TACR2POLB | |
| SCHEMBL3464223 | 0.85 | ALDH1A1 (0.72) | ALDH1A1KDM4EL3MBTL1TACR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3526199-B1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S R L (IT) | 2022-04-13 | — | — | EP | disclosed |
| EP-3885437-A1 | DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF, AND METHOD TO SYNTHESIZE THE LIBRARY | Technische Universität Dortmund (DE) | 2021-09-29 | — | — | EP | disclosed |
| US-20210230123-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2021-07-29 | — | — | US | disclosed |
| US-20180134667-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-05-17 | — | — | US | disclosed |
| WO-2018069532-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-04-19 | — | — | WO | disclosed |
| US-9077038-B2 | Lithium ion batteries | GM Global Technology Operations LLC (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130071742-A1 | LITHIUM ION BATTERIES | GM Global Technology Operations LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-5739163-A | ANTICOAGULANTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5523302-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230123-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | ALDH1A1 171/4885KDM4E 1110/4885L3MBTL1 2418/4885 |
| US-20180134667-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | ALDH1A1 171/4885KDM4E 1110/4885L3MBTL1 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.