Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25734135 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL5039573 | 0.75 | ENPP2 (0.39) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL29956241 | 0.75 | ENPP2 (0.39) | ALDH1A1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL29951146 | 0.75 | CCR1 (0.33) | ALDH1A1MAPTGAAAPLNR | |
| SCHEMBL16225239 | 0.75 | CCR1 (0.33) | ALDH1A1MAPTGAAAPLNR | |
| SCHEMBL31437468 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL29950629 | 0.74 | LRRK2 (0.37) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL29950703 | 0.74 | NFE2L2 (0.33) | KMT2AL3MBTL1MAPK1MAPTCYP3A4 | |
| SCHEMBL25728866 | 0.72 | SQOR (0.40) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL25463298 | 0.71 | HCRTR1 (0.39) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |