Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257567 | 1.00 | ALOX5 (0.67) | ALOX5CA1CA2CYP1A2LMNA | |
| SCHEMBL142665 | 0.84 | LMNA (0.66) | ALOX5CA1CA2CYP1A2LMNA | |
| SCHEMBL25278599 | 0.84 | MAOB (0.49) | ALOX5MAOBMAOA | |
| SCHEMBL31051012 | 0.84 | MAOB (0.49) | ALOX5MAOBMAOA | |
| SCHEMBL22315 | 0.83 | CYP4F2 (0.58) | ALOX5SRD5A2KDM4EALDH1A1RAB9A | |
| SCHEMBL23247030 | 0.83 | ALOX5 (0.53) | ALOX5CA1CA2CYP1A2LMNA | |
| SCHEMBL51460 | 0.81 | ALOX5 (1.00) | ALOX5CA1CA2CYP1A2LMNA | |
| SCHEMBL8984340 | 0.81 | ALOX5 (0.92) | ALOX5CA1CA2CYP1A2LMNA | |
| SCHEMBL13903287 | 0.81 | CYP1A2 (0.56) | ALOX5CA1CA2CYP1A2LMNA | |
| SCHEMBL2555201 | 0.80 | LMNA (0.59) | CA1CA2CYP1A2LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |