Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | LPL | P06858 | 3/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744338 | 1.00 | CA2 (0.43) | CA2LPLLIPGESR1CA1 | |
| SCHEMBL382234 | 0.79 | LPL (0.39) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL3790999 | 0.78 | GAA (0.52) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL6726431 | 0.78 | TTR (0.50) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL29817989 | 0.75 | CA2 (0.52) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL40868 | 0.75 | CA2 (0.52) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL21382152 | 0.73 | ENPP2 (0.37) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL3786524 | 0.73 | ENPP2 (0.41) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL3928671 | 0.73 | CA2 (0.50) | CA2LPLLIPGCA1ENPP2 | |
| SCHEMBL6561636 | 0.71 | ESR1 (0.47) | ESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |