Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056396 | 0.87 | ESR1 (0.40) | ESR1MCL1ALOX15CYP3A4ESR2 | |
| SCHEMBL8956467 | 0.81 | MCL1 (0.47) | ESR1MCL1ALOX15CYP3A4CHRM1 | |
| SCHEMBL11434258 | 0.78 | APP (0.55) | MCL1ALOX15CYP3A4ALDH1A1TSHR | |
| SCHEMBL20385011 | 0.76 | ACHE (0.43) | ESR1ALOX15CYP3A4CHRM1MAOA | |
| SCHEMBL11503436 | 0.75 | ALDH1A1 (0.44) | ESR1MCL1CYP3A4ESR2ALDH1A1 | |
| SCHEMBL1367532 | 0.75 | TDP1 (0.44) | ESR1ALOX15CYP3A4ALDH1A1TSHR | |
| SCHEMBL8123248 | 0.74 | MCL1 (0.46) | ESR1MCL1ALOX15ESR2ALDH1A1 | |
| SCHEMBL31418072 | 0.74 | MCL1 (0.46) | MCL1ALOX15ALDH1A1TSHRAPP | |
| SCHEMBL11409400 | 0.74 | ESR2 (0.38) | ESR1MCL1ALOX15CYP3A4CHRM1 | |
| SCHEMBL6515925 | 0.74 | CYP3A4 (0.41) | ESR1ALOX15CYP3A4CHRM1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301638-B1 | Improved process for producing n-alkyl-carbamates | ENICHEM SINTESI (IT) | 1993-12-08 | — | — | EP | claimed |
| US-5021590-A | Reacting alkyl isocyanates with phenols in solution using bicyclic amidine or guanidine catalyst | ENICHEM SYNTHESIS SPA (IT) | 1991-06-04 | — | — | US | claimed |
| EP-0190466-B1 | PROCESS FOR THE PRODUCTION OF N-METHYLCARBAMATES | ENICHEM SYNTHESIS S.p.A. (IT) | 1990-11-28 | — | — | EP | claimed |
| US-4659845-A | Process for the production of N-methylcarbamates | ENICHEM SINTESI S.P.A. (IT) | 1987-04-21 | — | — | US | claimed |
| EP-0190466-A1 | Process for the production of N-Methylcarbamates | ENICHEM SYNTHESIS S.p.A. (IT) | 1986-08-13 | — | — | EP | claimed |
| WO-2019183358-A2 | WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | WO | disclosed |
| EP-0992524-B1 | Process for preparing polyether polyols | BAYER AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6624321-B2 | Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| US-20030097026-A1 | Process for the preparation of polyether polyols | DENNINGER UWE (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6492565-B2 | USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | disclosed |
| US-20010053866-A1 | Process for the preparation of polyether polyols | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | US | disclosed |
| EP-0992524-A2 | Process for preparing polyether polyols | BAYER AG (DE) | 2000-04-12 | — | — | EP | disclosed |
| US-4211839-A | SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-08 | — | — | US | disclosed |
| EP-0007987-A1 | N-sulfenylated carbamoyloximino-1-methylthio butanes, process for their preparation and their use as insecticides | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| US-4188212-A | BEZNOTRIAZOLE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |
| EP-0005780-A1 | N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
| US-4163105-A | Aryloxymethyl imidazolines | THE DOW CHEMICAL COMPANY (US) | 1979-07-31 | — | — | US | disclosed |
| US-4122089-A | Aminothiofluoran compounds, process for the production thereof, and recording elements containing the same | SANKIO CHEMICAL CO., LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
| US-4020084-A | Cyclic aminals of aromatic aldehydes | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-26 | — | — | US | disclosed |
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097026-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | ESR1 640/4885MCL1 510/4885ALOX15 274/4885 |
| US-20010053866-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | ESR1 640/4885MCL1 510/4885ALOX15 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.