Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951768 | 0.85 | MAOA (0.39) | HPGDMAOALMNAALDH1A1MAPT | |
| SCHEMBL2561584 | 0.81 | ALDH1A1 (0.40) | LMNAALDH1A1GAA | |
| SCHEMBL2556451 | 0.79 | ALDH1A1 (0.42) | HPGDLMNAALDH1A1GAA | |
| SCHEMBL29952930 | 0.78 | ALDH1A1 (0.45) | MAOALMNAALDH1A1MAPTGAA | |
| SCHEMBL2561754 | 0.78 | ALDH1A1 (0.41) | HPGDLMNAALDH1A1MAPTGAA | |
| SCHEMBL2555782 | 0.77 | MEN1 (0.35) | LMNAALDH1A1MAPTGAAGRIN2B | |
| SCHEMBL29952559 | 0.76 | MAOA (0.43) | HPGDMAOALMNAALDH1A1MAPT | |
| SCHEMBL29956614 | 0.76 | LMNA (0.43) | HPGDMAOALMNAMAPTGRIN2B | |
| SCHEMBL2555463 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL29956007 | 0.71 | MAOA (0.49) | MAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |