Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956614 | 0.83 | LMNA (0.43) | MAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2561856 | 0.81 | OPRM1 (0.41) | KMT2AMEN1SMN1; SMN2TSHRGAA | |
| SCHEMBL29952270 | 0.81 | TSHR (0.51) | MAOAKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL29957679 | 0.78 | NOTUM (0.39) | KMT2AMEN1SMN1; SMN2TSHROPRM1 | |
| SCHEMBL29952559 | 0.77 | MAOA (0.43) | MAOAKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL2559106 | 0.77 | MEN1 (0.45) | KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL29953800 | 0.76 | MAPT (0.40) | MAOAKMT2AMEN1TSHRGAA | |
| SCHEMBL2553177 | 0.76 | TSHR (0.43) | KMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL29952930 | 0.76 | ALDH1A1 (0.45) | MAOAKMT2AGAA | |
| SCHEMBL29951768 | 0.76 | MAOA (0.39) | MAOAKMT2AMEN1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |