Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LPL | P06858 | 6/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114706 | 0.80 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL171719 | 0.80 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL2386907 | 0.79 | LPL (0.58) | ALDH1A1LPLLIPGCA1CA2 | |
| SCHEMBL17923187 | 0.79 | LPL (0.41) | ALDH1A1POLBMAPTSMN1; SMN2LPL | |
| SCHEMBL24723659 | 0.78 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL2238302 | 0.78 | ALDH1A1 (0.69) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL6412640 | 0.78 | ALDH1A1 (0.68) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL2760548 | 0.78 | RIPK1 (0.60) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL23997228 | 0.78 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 | |
| SCHEMBL3132202 | 0.78 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |