SCHEMBL2386907

SCHEMBL2386907

CN(C)Cc1ccc(B(O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.58
LIPG Q9Y5X9 7/20 0.58
HRH3 Q9Y5N1 2/20 0.56
CA2 P00918 4/20 0.50
CA1 P00915 3/20 0.50
TSHR P16473 2/20 0.50
F11 P03951 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
TRPV1 Q8NER1 1/20 0.47
MGLL Q99685 1/20 0.47
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
ENPP2 Q13822 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3109951 0.98 LPL (0.56) LPLLIPGHRH3CA2CA1
SCHEMBL659509 0.80 HRH3 (0.82) HRH3TSHRALDH1A1TAAR1NOS3
SCHEMBL7197772 0.79 LPL (0.50) LPLLIPGHRH3CA2CA1
SCHEMBL12663150 0.79 LPL (0.50) LPLLIPGCA2CA1TSHR
SCHEMBL29954820 0.79 ALDH1A1 (0.57) LPLLIPGCA2CA1F11
SCHEMBL28451270 0.78 LPL (0.59) LPLLIPGHRH3CA2CA1
SCHEMBL2554733 0.78 LPL (0.61) LPLLIPGHRH3CA2CA1
SCHEMBL19697830 0.78 PYCR1 (0.51) LPLLIPGCA2CA1F11
Hydrochloric Acid SCHEMBL3337542 0.77 LPL (0.57) LPLLIPGHRH3CA2CA1
SCHEMBL4802780 0.77 ENPP2 (0.48) LPLLIPGCA2CA1F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240173-B Preparation process of high-strength polyurethane heat-insulating material 优佰特(山东)新材料技术有限公司 2024-07-16 CN claimed
CN-118240173-A Preparation process of high-strength polyurethane heat-insulating material 优佰特(山东)新材料技术有限公司 2024-06-25 CN claimed
EP-4716685-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2026-04-01 EP disclosed
US-20260070906-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2026-03-12 US disclosed
US-12441702-B2 Substituted 4-benzyl and 4-benzoyl piperidine derivates CEPHALON LLC (US) 2025-10-14 US disclosed
US-20250170138-A1 ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS Epizyme, Inc. 2025-05-29 US disclosed
US-20250059182-A1 SOS1 INHIBITORS MIRATI THERAPEUTICS, INC 2025-02-20 US disclosed
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-01-14 US disclosed
US-12168015-B2 Aryl-or heteroaryl-substituted benzene compounds Epizyme, Inc. (US) 2024-12-17 US disclosed
US-12168016-B2 Aryl-OR heteroaryl-substituted benzene compounds Epizyme, Inc. (US) 2024-12-17 US disclosed
US-12161645-B2 Aryl-or heteroaryl-substituted benzene compounds Epizyme, Inc. (US) 2024-12-10 US disclosed
US-20080076778-A1 METHODS FOR DESIGNING PARP INHIBITORS AND USES THEREOF BIPAR SCIENCES, INC. (US) 2008-03-27 US disclosed
US-20080004308-A1 AZAINDOLE INHIBITORS OF AURORA KINASES GLAXOSMITHKLINE LLC 2008-01-03 US disclosed
US-7282588-B2 Azaindole inhibitors of aurora kinases SMITHKLINE BEECHAM (US) 2007-10-16 US disclosed
US-20070149561-A1 AZAINDOLE INHIBITORS OF AURORA KINASES GLAXOSMITHKLINE LLC 2007-06-28 US disclosed
US-20050261263-A1 Benzoquinone ansamycins KOSAN BIOSCIENCES, INC. 2005-11-24 US disclosed
US-6872715-B2 Benzoquinone ansamycins KOSAN BIOSCIENCES, INC. (US) 2005-03-29 US disclosed
EP-1420747-A2 BENZOQUINONE ANSAMYCINS Kosan Biosciences, Inc. (US) 2004-05-26 EP disclosed
US-20030114450-A1 Anticancer agents; antiproliferative agent KOSAN BIOSCIENCES, INC. 2003-06-19 US disclosed
WO-2003013430-A2 BENZOQUINONE ANSAMYCINS KOSAN BIOSCIENCES, INC. (US) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12168016-B2 Aryl-OR heteroaryl-substituted benzene compounds AHR, ARNT, CYP1B1 LPL 2073/4885LIPG 2686/4885HRH3 756/4885
US-12441702-B2 Substituted 4-benzyl and 4-benzoyl piperidine derivates FASN, CES1, FADS2 LPL 175/4885LIPG 152/4885HRH3 3776/4885
US-20070149561-A1 AZAINDOLE INHIBITORS OF AURORA KINASES AURKA, AURKC, AURKB LPL 4835/4885LIPG 4630/4885HRH3 2284/4885
US-20080076778-A1 METHODS FOR DESIGNING PARP INHIBITORS AND USES THEREOF PARP3, PARP1, PARP15 LPL 3745/4885LIPG 3349/4885HRH3 3600/4885
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC LPL 3708/4885LIPG 1899/4885HRH3 2012/4885
US-20030114450-A1 Anticancer agents; antiproliferative agent HSP90AB1, HSP90B1, HSP90AA1 LPL 3713/4885LIPG 3634/4885HRH3 4253/4885
US-12161645-B2 Aryl-or heteroaryl-substituted benzene compounds AHR, ARNT, CYP1B1 LPL 2073/4885LIPG 2686/4885HRH3 756/4885
US-20250059182-A1 SOS1 INHIBITORS SOS1, SOS2, SOST LPL 4267/4885LIPG 3733/4885HRH3 3894/4885
US-20050261263-A1 Benzoquinone ansamycins HSP90B1, HSP90AB1, HSP90AB2P LPL 3841/4885LIPG 3774/4885HRH3 4148/4885
US-20250170138-A1 ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS AHR, ARNT, CYP1B1 LPL 2073/4885LIPG 2686/4885HRH3 756/4885
US-20260070906-A1 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER TLR1, TLR6, TLR8 LPL 2712/4885LIPG 3253/4885HRH3 240/4885
US-20080004308-A1 AZAINDOLE INHIBITORS OF AURORA KINASES AURKA, AURKC, AURKB LPL 4835/4885LIPG 4630/4885HRH3 2284/4885
US-12168015-B2 Aryl-or heteroaryl-substituted benzene compounds AHR, ARNT, CYP1B1 LPL 2073/4885LIPG 2686/4885HRH3 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.