Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954881 | 0.87 | NOTUM (0.52) | DRD2KDM4ECYP2C19HSD17B10USP2 | |
| SCHEMBL24712493 | 0.79 | MEN1 (0.54) | DRD2KDM4ECYP2C19HSD17B10USP2 | |
| SCHEMBL22807134 | 0.79 | RBP4 (0.53) | KDM4ECYP2C19HPGDNOTUMSCN9A | |
| SCHEMBL22807115 | 0.77 | KDM4E (0.56) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL24712501 | 0.74 | CYP2C19 (0.43) | DRD2KDM4ECYP2C19HPGDTSHR | |
| SCHEMBL2557896 | 0.74 | NOTUM (0.52) | KDM4ECYP2C19NOTUMNEK2APAF1 | |
| SCHEMBL24712509 | 0.74 | KDM4E (0.59) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL24712497 | 0.73 | KDM4E (0.42) | DRD2KDM4ECYP2C19HSD17B10USP2 | |
| SCHEMBL29956491 | 0.72 | NOTUM (0.55) | DRD2KDM4EHSD17B10NOTUMMAPT | |
| SCHEMBL24712508 | 0.71 | KDM4E (0.59) | KDM4ECYP2C19HSD17B10USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267303-A1 | Compounds and Methods for Treating or Preventing Bacterial Infections | BAYLOR COLLEGE OF MEDICINE | 2022-08-25 | — | — | US | disclosed |
| WO-2020257734-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING BACTERIAL INFECTIONS | BAYLOR COLLEGE OF MEDICINE (US) | 2020-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267303-A1 | Compounds and Methods for Treating or Preventing Bacterial Infections | OXA1L, MMP8, OGG1 | DRD2 3147/4885KDM4E 1801/4885CYP2C19 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.