Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 14/20 | 1.00 |
| ▸ | HSPA1A | P0DMV8 | 13/20 | 1.00 |
| ▸ | NR4A1 | P22736 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.73 |
| ▸ | MASP2 | O00187 | 3/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | NSD2 | O96028 | 1/20 | 0.73 |
| ▸ | ALPL | P05186 | 1/20 | 0.73 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.73 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.73 |
| ▸ | GAPDH | P04406 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | BLM | P54132 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706084 | 0.84 | POLB (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL13186581 | 0.79 | PTPN7 (0.73) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL2808722 | 0.79 | PTPN7 (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL16706087 | 0.79 | PTPN7 (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL25602294 | 0.76 | USP7 (0.67) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL31492743 | 0.76 | PTPN7 (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL26098723 | 0.76 | PTPN7 (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL17211738 | 0.75 | HSPA1A (0.81) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL15033517 | 0.74 | POLB (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A | |
| SCHEMBL1066515 | 0.74 | PTPN7 (1.00) | PTPN7HSPA1ANR4A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2009073550-A2 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | NISCH, NDUFS3, SDHA | PTPN7 3898/4885HSPA1A 581/4885NR4A1 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.