Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.63 |
| ▸ | ERN1 | O75460 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535520 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL12672585 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL29957021 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL22629206 | 0.82 | CYP1A2 (0.47) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL135243 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL437463 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL1236491 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL96291 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL134251 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL16381877 | 0.79 | ALDH1A1 (0.76) | ALDH1A1TRIM24TYRTRIM33ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |