Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.63 |
| ▸ | ERN1 | O75460 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12672585 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL29957021 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL1236491 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL437463 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL135243 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL29954936 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL96291 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL18535520 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL16381877 | 0.79 | ALDH1A1 (0.76) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL133876 | 0.78 | TYR (1.00) | ALDH1A1TRIM24TYRTRIM33ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048295-A1 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF | JANSSEN PHARMACEUTICE N.V. (BE) | 2009-02-19 | — | — | US | claimed |
| CN-107011132-B | Aromatic compound containing branched chain | 味之素株式会社 | 2020-11-10 | — | — | CN | disclosed |
| CN-107011131-B | Aromatic compound containing branched chain | 味之素株式会社 | 2020-11-10 | — | — | CN | disclosed |
| EP-2612845-B1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | AJINOMOTO KK (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-10711033-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2020-07-14 | — | — | US | disclosed |
| CN-106220482-B | Aromatic compound containing branched chain | 味之素株式会社 | 2020-01-07 | — | — | CN | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20140005359-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-01-02 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| EP-2612845-A1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | Ajinomoto Co., Inc. (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20090048295-A1 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF | JANSSEN PHARMACEUTICE N.V. (BE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048295-A1 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF | C3AR1, C5AR1, C5AR2 | ALDH1A1 3130/4885TRIM24 4131/4885TYR 751/4885 |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | ALDH1A1 3695/4885TRIM24 181/4885TYR 167/4885 |
| US-10711033-B2 | Branched chain-containing aromatic compound | VIP, IAPP, BCAT1 | ALDH1A1 3285/4885TRIM24 131/4885TYR 114/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | ALDH1A1 3285/4885TRIM24 131/4885TYR 114/4885 |
| US-20140005359-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | ALDH1A1 3285/4885TRIM24 131/4885TYR 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.