Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953938 | 0.75 | HSD17B1 (0.54) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL5292685 | 0.75 | ALDH1A1 (0.56) | SMN1; SMN2CA1CA2ALDH1A1HPGD | |
| SCHEMBL171843 | 0.75 | ACHE (0.52) | LMNASMN1; SMN2ALDH1A1LPAR1 | |
| SCHEMBL23114 | 0.74 | ENPP2 (0.52) | ENPP2CA1CA2ALDH1A1HPGD | |
| SCHEMBL29127764 | 0.74 | ENPP2 (0.44) | ENPP2CA1CA2KDRTUBB4A | |
| SCHEMBL5636990 | 0.72 | ENPP2 (0.42) | ENPP2CA1CA2TUBB4ATUBB | |
| SCHEMBL25173988 | 0.72 | ENPP2 (0.54) | ENPP2CA1CA2KDRTUBB4A | |
| SCHEMBL28900181 | 0.71 | GAA (0.47) | LMNASMN1; SMN2ALDH1A1HPGDCYP1A1 | |
| SCHEMBL11322 | 0.71 | MAOB (0.57) | LMNAENPP2CA1CA2ALDH1A1 | |
| SCHEMBL29956693 | 0.71 | MAOB (0.57) | LMNAENPP2CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |