SCHEMBL29955036

SCHEMBL29955036

[C-]#[N+]c1ccc(Cl)cc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 1/20 0.39
AR P10275 13/20 0.38
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
CSNK1D P48730 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956599 0.78 AR (0.46) AR
Hydrochloric Acid SCHEMBL10834372 0.77 RAB9A (0.37) CYP1A2CYP2D6CYP2C19RAB9AAR
SCHEMBL12378214 0.76 GAA (0.55) ARKDM4E
SCHEMBL29951072 0.76 KDM1A (0.42) AR
SCHEMBL9264759 0.76 GAA (0.55) ARKDM4E
SCHEMBL7119172 0.73 P2RX7 (0.34) AR
SCHEMBL3789153 0.73 CYP3A4 (0.52) CYP1A2CYP2D6CYP2C19RAB9AAR
SCHEMBL29954160 0.72 CCR2 (0.34)
SCHEMBL12125524 0.72 AR (0.39) AR
SCHEMBL12552106 0.72 TP53 (0.48) CYP1A2CYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed