Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3522137 | 0.87 | TDP1 (0.34) | APPLMNATDP1TSHRMAPT | |
| SCHEMBL20599942 | 0.87 | LMNA (0.50) | LMNATDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL18399227 | 0.86 | ALDH1A1 (0.33) | APPLMNATDP1TSHRMAPT | |
| SCHEMBL29956166 | 0.76 | ALDH1A1 (0.46) | APPTDP1TSHRMAPTALDH1A1 | |
| SCHEMBL4976296 | 0.74 | ALDH1A1 (0.39) | LMNAMAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL29956745 | 0.72 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26418162 | 0.70 | ALDH1A1 (0.35) | LMNATDP1TSHRMAPTMEN1 | |
| SCHEMBL20773114 | 0.70 | MAPT (0.40) | APPTSHRMAPTMEN1KMT2A | |
| SCHEMBL21518219 | 0.70 | PDE2A (0.39) | APPLMNATDP1MAPTKMT2A | |
| SCHEMBL8127634 | 0.70 | L3MBTL1 (0.40) | APPLMNATDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |