SCHEMBL4537

SCHEMBL4537

CN(C)Cc1ccccc1B(O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.50
SLC6A4 P31645 13/20 0.44
SLC6A2 P23975 10/20 0.44
SLC6A3 Q01959 9/20 0.43
HTR2A P28223 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
LMNA P02545 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
G6PD P11413 1/20 0.41
PABPC1 P11940 1/20 0.41
KMT2A Q03164 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504654 1.00 LIPG (0.50) LIPGSLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL14753645 0.83 LIPG (0.47) LIPGALDH1A1TSHRKDM4E
SCHEMBL17345424 0.83 SLC6A4 (0.44) SLC6A4SLC6A2SLC6A3HTR2AALDH1A1
SCHEMBL29955063 0.80 LIPG (0.44) LIPGALDH1A1LMNAKDM4EMEN1
SCHEMBL29592212 0.79 LIPG (0.52) LIPGALDH1A1TSHRLMNAKDM4E
SCHEMBL6771506 0.79 LIPG (0.56) LIPGHTR2A
SCHEMBL1133300 0.79 LIPG (0.52) LIPGALDH1A1TSHRLMNAKDM4E
SCHEMBL4695639 0.79 ALDH1A1 (0.55) LIPGALDH1A1TSHRLMNAKDM4E
SCHEMBL29956436 0.79 ALDH1A1 (0.55) LIPGALDH1A1TSHRLMNAKDM4E
SCHEMBL125255 0.78 ALDH1A1 (0.57) SLC6A4SLC6A2SLC6A3HTR2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271090-B Method for improving isostatic graphite and isostatic graphite prepared by same 湖南德智新材料有限公司 2024-07-26 CN claimed
CN-118271090-A Method for improving isostatic graphite and isostatic graphite prepared by same 湖南德智新材料有限公司 2024-07-02 CN claimed
EP-3039403-B1 METHOD FOR DETECTING TRANSPARENT EXOPOLYMER PARTICLES IN A WATER SAMPLE KEMIRA OYJ (FI) 2018-06-20 EP claimed
US-9884074-B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications EYEON PARTICLE SCIENCES LLC (US) 2018-02-06 US claimed
US-20160243156-A1 Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications CALM WATER THERAPEUTICS LLC 2016-08-25 US claimed
US-20160202189-A1 Method for detecting transparent exopolymer particles in a water sample KEMIRA OYJ (FI) 2016-07-14 US claimed
EP-3039403-A1 METHOD FOR DETECTING TRANSPARENT EXOPOLYMER PARTICLES IN A WATER SAMPLE Kemira Oyj (FI) 2016-07-06 EP claimed
WO-2015028711-A1 METHOD FOR DETECTING TRANSPARENT EXOPOLYMER PARTICLES IN A WATER SAMPLE KEMIRA OYJ (FI) 2015-03-05 WO claimed
US-8946476-B2 Process for the preparation of amino acid derivatives UCB PHARMA GMBH (DE) 2015-02-03 US claimed
US-8501993-B2 Processes for the preparation of amides SYNGENTA LIMITED (GB) 2013-08-06 US claimed
US-20110178310-A1 PROCESS FOR THE PREPARATION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-07-21 US claimed
US-20110071315-A1 PROCESSES FOR THE PREPARATION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-03-24 US claimed
EP-2280944-A1 PROCESS FOR THE PREPARATION OF AMIDES Syngenta Limited (GB) 2011-02-09 EP claimed
WO-2009138375-A1 PROCESS FOR THE PREPARATION OF AMIDES SYNGENTA LIMITED (GB) 2009-11-19 WO claimed
US-7029688-B2 Methods and compositions to prevent formation of adhesions in biological tissues CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-18 US claimed
EP-1009451-B1 COMPOSITIONS AND THEIR USE TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES CALIFORNIA INST OF TECHN (US) 2003-10-29 EP claimed
US-20030185787-A1 Methods and compositions to prevent formation of adhesions in biological tissues CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-10-02 US claimed
US-6596267-B1 Such as ethylene glycol-phenylboronic acid copolymer; prosthetics and implant coatings; readily adsorbs onto body tissues in situ providing steric barrier minimizing post-operative adhesion CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-07-22 US claimed
EP-1009451-A2 METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-06-21 EP claimed
WO-1999010022-A2 METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1999-03-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071315-A1 PROCESSES FOR THE PREPARATION OF AMIDES PAH, CYP3A4, AKR7A2 LIPG 3235/4885SLC6A4 1673/4885SLC6A2 1250/4885
US-20030185787-A1 Methods and compositions to prevent formation of adhesions in biological tissues ITGB6, ITGA6, EPCAM LIPG 831/4885SLC6A4 4041/4885SLC6A2 2262/4885
US-20110178310-A1 PROCESS FOR THE PREPARATION OF AMIDES H1-5, CYP3A5, CYP2B6 LIPG 2947/4885SLC6A4 2345/4885SLC6A2 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.