SCHEMBL29953331

SCHEMBL29953331

CNC(=O)CN(C)CCC=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31
MCL1 Q07820 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952363 0.81 MCL1 (0.34) ALDH1A1HPGDMCL1
SCHEMBL29955601 0.79 TSHR (0.35) ALDH1A1HPGDLMNA
SCHEMBL29951830 0.79 OPRM1 (0.36) ALDH1A1OPRM1OPRL1MCL1LMNA
SCHEMBL29953702 0.78 MCL1 (0.38) ALDH1A1MCL1
SCHEMBL13567026 0.78 MCL1 (0.40) ALDH1A1HPGDOPRM1OPRL1MCL1
SCHEMBL29954294 0.77 ALDH1A1 (0.33) ALDH1A1HPGDLMNA
SCHEMBL13348004 0.77 KDM5A (0.37) ALDH1A1HPGDOPRM1OPRL1MCL1
SCHEMBL11617336 0.77 MAPT (0.36) ALDH1A1HPGDOPRM1OPRL1MCL1
SCHEMBL8363255 0.77 CA12 (0.43) ALDH1A1HPGDOPRM1OPRL1MCL1
SCHEMBL29952336 0.77 LMNA (0.40) ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed