Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358403 | 0.78 | PTPN1 (1.00) | PTPN1MAOAMAOBMEN1POLB | |
| SCHEMBL29955707 | 0.72 | PTPN1 (0.72) | PTPN1MAOAMAOBMEN1POLB | |
| SCHEMBL1984098 | 0.72 | AHR (0.43) | MAOAMAOB | |
| SCHEMBL7025065 | 0.67 | PTPN1 (0.70) | PTPN1MAOAMAOBMEN1POLB | |
| SCHEMBL23887130 | 0.65 | PTPN1 (0.72) | PTPN1MAOAMAOBMEN1POLB | |
| SCHEMBL5363245 | 0.65 | PTPN1 (1.00) | PTPN1MAOAMAOBPOLBKMT2A | |
| SCHEMBL4596158 | 0.64 | AHR (0.43) | — | |
| SCHEMBL30307600 | 0.62 | PTPN1 (0.62) | PTPN1MAOAMAOBMEN1POLB | |
| SCHEMBL5708656 | 0.62 | PTPN1 (1.00) | PTPN1MAOAMAOBMEN1POLB | |
| SCHEMBL29958044 | 0.62 | PTPN1 (0.77) | PTPN1MAOAMAOBMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |