Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556848 | 0.88 | ALOX5 (0.39) | ABCB1MAPTPTGESALOX5SMN1; SMN2 | |
| SCHEMBL29951636 | 0.88 | TNKS2 (0.44) | ABCB1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15330118 | 0.87 | KDM4E (0.44) | MAPTPTGESALOX5KDM4ENPC1 | |
| SCHEMBL2559575 | 0.86 | PTGES (0.37) | MAPTPTGESALOX5KDM4ENPC1 | |
| SCHEMBL29951123 | 0.84 | MAPT (0.42) | ABCB1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL29957073 | 0.84 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2NPC1ALDH1A1TDP1 | |
| SCHEMBL15329681 | 0.84 | SMN1; SMN2 (0.42) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2563854 | 0.82 | PTGES (0.37) | MAPTPTGESALOX5KDM4ENPC1 | |
| SCHEMBL15329748 | 0.81 | ERN1 (0.40) | ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL15330604 | 0.81 | MAPT (0.40) | ABCB1MAPTPTGESALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |