Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556051 | 0.91 | ALDH1A1 (0.46) | SIGMAR1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL2560626 | 0.89 | GNAI3 (0.40) | ALDH1A1GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL2557614 | 0.85 | ALDH1A1 (0.52) | SIGMAR1ALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL27731632 | 0.84 | HTT (0.41) | SIGMAR1ALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL15331209 | 0.84 | ALDH1A1 (0.49) | SIGMAR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29952645 | 0.83 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL6897984 | 0.82 | ALDH1A1 (0.57) | SIGMAR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2559238 | 0.81 | TSHR (0.46) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL2555755 | 0.81 | ALDH1A1 (0.62) | SIGMAR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2555452 | 0.81 | ALDH1A1 (0.42) | SIGMAR1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |