Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16856823 | 0.73 | LMNA (0.44) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL7125030 | 0.71 | L3MBTL1 (0.41) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL16857291 | 0.69 | TOP2A (0.38) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL29956074 | 0.69 | KDM4E (0.39) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL16857151 | 0.69 | TOP2A (0.38) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL16377909 | 0.69 | KDM4E (0.39) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL16857014 | 0.69 | LMNA (0.34) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL22208034 | 0.68 | LMNA (0.45) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL16856956 | 0.68 | TOP2A (0.38) | LMNAKDM4ETOP2AL3MBTL1CETP | |
| SCHEMBL31146097 | 0.67 | L3MBTL1 (0.42) | LMNAKDM4ETOP2AL3MBTL1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |