Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635180 | 0.76 | KMT2A (0.50) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL13144468 | 0.76 | SQOR (0.57) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL29957427 | 0.75 | JAK2 (0.38) | KMT2AMEN1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16638841 | 0.75 | KMT2A (0.49) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL29954219 | 0.75 | RPS6KA3 (0.41) | KMT2AMEN1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29951146 | 0.74 | CCR1 (0.33) | MAPTALDH1A1DYRK1AAURKBENPP2 | |
| SCHEMBL29956241 | 0.74 | ENPP2 (0.39) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL5039573 | 0.74 | ENPP2 (0.39) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL16225239 | 0.74 | CCR1 (0.33) | MAPTALDH1A1DYRK1AAURKBENPP2 | |
| SCHEMBL29950703 | 0.73 | NFE2L2 (0.33) | KMT2AMAPTL3MBTL1DYRK1AAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |