Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951935 | 0.94 | ALDH1A3 (0.50) | HPGDSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL29952000 | 0.86 | HPGD (0.55) | HPGDSMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL25894347 | 0.82 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL29954591 | 0.80 | TSHR (0.49) | HPGDSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL2557252 | 0.80 | ALDH1A3 (0.56) | HPGDALDH1A1ALDH1A3 | |
| SCHEMBL2558483 | 0.78 | ALDH1A3 (0.58) | SMN1; SMN2ALDH1A1ALDH1A3KMT2A | |
| SCHEMBL16083180 | 0.77 | ATF4 (0.52) | HPGDSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL29956063 | 0.76 | HPGD (0.70) | HPGDSMN1; SMN2ALDH1A1TSHRPOLB | |
| SCHEMBL1811263 | 0.76 | ALDH1A3 (0.63) | HPGDSMN1; SMN2NPSR1ALDH1A1ALDH1A3 | |
| SCHEMBL10455042 | 0.76 | ALDH1A3 (0.63) | HPGDSMN1; SMN2NPSR1ALDH1A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |