Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954814 | 0.83 | HPGD (0.40) | HPGDKDM4EALDH1A1TDP1GAA | |
| SCHEMBL29956080 | 0.82 | HPGD (0.58) | HPGDKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2564466 | 0.81 | TSHR (0.40) | HPGDKDM4EALDH1A1MAPK1CASP1 | |
| SCHEMBL1642006 | 0.80 | ALOX5 (0.50) | HPGDKDM4EALDH1A1MAPK1TDP1 | |
| SCHEMBL29956903 | 0.80 | ALOX5 (0.50) | HPGDKDM4EALDH1A1MAPK1TDP1 | |
| SCHEMBL29956003 | 0.78 | CNR1 (0.51) | TDP1GAAL3MBTL1ADRB2ADRB1 | |
| SCHEMBL7675242 | 0.78 | MAPT (0.42) | HPGDKDM4EALDH1A1TDP1GAA | |
| SCHEMBL23666003 | 0.77 | L3MBTL1 (0.62) | HPGDKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2556411 | 0.77 | NCF1 (0.46) | KDM4EALDH1A1MAPK1TDP1GAA | |
| SCHEMBL15330334 | 0.77 | KDM1A (0.42) | HPGDKDM4EALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |