Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12847220 | 0.87 | MGLL (0.40) | NPSR1MGLLCYP2C9SCN8ASCN10A | |
| SCHEMBL29952234 | 0.87 | MGLL (0.40) | NPSR1MGLLCYP2C9SCN8ASCN10A | |
| SCHEMBL319585 | 0.81 | ENPP2 (0.47) | MEN1MAPTKMT2ANPSR1MGLL | |
| SCHEMBL29588618 | 0.81 | ENPP2 (0.47) | MEN1MAPTKMT2ANPSR1MGLL | |
| SCHEMBL2101703 | 0.80 | PTGDR2 (0.53) | KMT2AFFAR1MGLLCYP2C19KDM4E | |
| SCHEMBL16959475 | 0.79 | BACE1 (0.47) | MEN1LMNAMAPTHTTKMT2A | |
| SCHEMBL15010805 | 0.77 | HTT (0.36) | MEN1MAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29956290 | 0.77 | ALDH1A1 (0.49) | MEN1LMNAMAPTHTTKMT2A | |
| SCHEMBL29952656 | 0.77 | HTT (0.36) | MEN1MAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29950647 | 0.77 | CYP1A2 (0.55) | MEN1LMNAMAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |