Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15193542 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1KMT2APARP10HPGD | |
| SCHEMBL29636289 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1KMT2APARP10HPGD | |
| SCHEMBL25329078 | 0.76 | CA1 (0.46) | ALDH1A1TDP1KMT2APARP10HPGD | |
| SCHEMBL1326006 | 0.76 | ENPP2 (0.48) | ALDH1A1KMT2AHPGDKDM4EFFAR4 | |
| Water SCHEMBL29952981 | 0.74 | ENPP2 (0.46) | ALDH1A1KMT2AHPGDKDM4EFFAR4 | |
| SCHEMBL19940003 | 0.73 | PLAU (0.42) | ALDH1A1TDP1KMT2APARP10HPGD | |
| SCHEMBL29955737 | 0.72 | ENPP2 (0.36) | ALDH1A1KMT2APARP10GRIN2DGRIN3B | |
| SCHEMBL15828893 | 0.71 | L3MBTL1 (0.43) | ALDH1A1TDP1HPGDKDM4EHSD17B10 | |
| SCHEMBL10153872 | 0.71 | TDP1 (0.62) | ALDH1A1TDP1KMT2APARP10HPGD | |
| SCHEMBL24105910 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TDP1KMT2APARP10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |