Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954830 | 0.88 | MAPT (0.38) | MAPTALDH1A1HTTLMNATP53 | |
| SCHEMBL29952427 | 0.79 | EPHX2 (0.40) | SMN1; SMN2PIM1PIM2MAPTALDH1A1 | |
| SCHEMBL12727796 | 0.79 | PGR (0.50) | SMN1; SMN2MAPTALDH1A1LMNATP53 | |
| SCHEMBL29952126 | 0.78 | MAOB (0.43) | SMN1; SMN2PIM1PIM2MAPTALDH1A1 | |
| SCHEMBL2056355 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1HTTTDP1 | |
| SCHEMBL29953205 | 0.76 | PGR (0.43) | MAPTLMNATP53PGRMEN1 | |
| SCHEMBL29954649 | 0.76 | TP53 (0.46) | SMN1; SMN2MAPTALDH1A1LMNATP53 | |
| SCHEMBL1314441 | 0.76 | HTR7 (0.40) | PIM1PIM2MAPTKMT2A | |
| SCHEMBL22419352 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTALDH1A1HTTTDP1 | |
| SCHEMBL18898645 | 0.75 | MAOB (0.51) | SMN1; SMN2MAPTALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |