Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956445 | 0.88 | SMN1; SMN2 (0.40) | MAPTTP53LMNAADAMTS5KDM4E | |
| SCHEMBL29952427 | 0.76 | EPHX2 (0.40) | MAPTKDM4EGAAPGRMEN1 | |
| SCHEMBL29952126 | 0.75 | MAOB (0.43) | MAPTTP53LMNAKDM4EMEN1 | |
| SCHEMBL29954649 | 0.73 | TP53 (0.46) | MAPTTP53LMNAALDH1A1 | |
| SCHEMBL1314441 | 0.73 | HTR7 (0.40) | MAPTKMT2A | |
| SCHEMBL29953205 | 0.73 | PGR (0.43) | MAPTTP53LMNAPGRMEN1 | |
| SCHEMBL29951858 | 0.73 | MAOA (0.48) | MAPTTP53LMNAGAAL3MBTL1 | |
| SCHEMBL29055652 | 0.69 | ESR1 (0.41) | MAPTTP53LMNAKDM4EALDH1A1 | |
| SCHEMBL1101964 | 0.69 | IDO1 (0.47) | MAPTTP53KDM4EGAAL3MBTL1 | |
| SCHEMBL29951005 | 0.69 | IDO1 (0.47) | MAPTTP53KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |