Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407367 | 0.84 | DHFR (0.39) | TAAR1ALDH1A1CYP2D6MAOBDHFR | |
| SCHEMBL29956321 | 0.79 | TAAR1 (0.57) | TAAR1IDO1ACHEHRH3MAOB | |
| SCHEMBL29954468 | 0.77 | IDH1 (0.35) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL12629117 | 0.77 | PGK1 (0.38) | — | |
| SCHEMBL8758778 | 0.75 | — | — | |
| SCHEMBL5571181 | 0.75 | — | — | |
| SCHEMBL2992299 | 0.74 | PNMT (0.54) | TAAR1IDO1 | |
| SCHEMBL29951474 | 0.74 | TAAR1 (0.50) | TAAR1IDO1ALDH1A1MAOBMEN1 | |
| SCHEMBL29951478 | 0.74 | TAAR1 (0.50) | TAAR1IDO1CYP2D6MAOBCYP11B1 | |
| SCHEMBL29953051 | 0.74 | PNMT (0.54) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |