Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951478 | 0.84 | TAAR1 (0.50) | CYP1A2TAAR1SIGMAR1CYP2D6MAOB | |
| SCHEMBL29956498 | 0.84 | TAAR1 (0.50) | DHFRMEN1KMT2ATAAR1CYP2D6 | |
| SCHEMBL5452057 | 0.84 | TAAR1 (0.50) | MEN1KMT2ATAAR1SLC6A4SLC6A3 | |
| SCHEMBL29953051 | 0.84 | PNMT (0.54) | TAAR1SIGMAR1PNMT | |
| SCHEMBL2992299 | 0.84 | PNMT (0.54) | TAAR1SIGMAR1PNMT | |
| SCHEMBL1550703 | 0.84 | TAAR1 (0.50) | CYP1A2TAAR1SIGMAR1CYP2D6MAOB | |
| SCHEMBL29951474 | 0.84 | TAAR1 (0.50) | MEN1KMT2ATAAR1SLC6A4SLC6A3 | |
| SCHEMBL13015764 | 0.83 | ENPP2 (0.49) | DHFRMEN1KMT2ACYP1A1CYP1A2 | |
| SCHEMBL168131 | 0.80 | — | — | |
| SCHEMBL29954868 | 0.79 | HTR2A (0.56) | MEN1KMT2AGRIN2BTAAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674128-B2 | Conductive organometallic framework | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-18 | — | — | US | claimed |
| US-20120017668-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-26 | — | — | US | claimed |
| EP-2382043-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | The Regents of the University of California (US) | 2011-11-02 | — | — | EP | claimed |
| WO-2010083418-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-22 | — | — | WO | claimed |
| US-4169030-A | PRODUCTION OF HYDROGEN FUEL BY SOLAR PHOTOLYSIS OF WATER | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1979-09-25 | — | — | US | claimed |
| CN-117396530-A | Polymerization of silane-modified polymers produced by free-radical chain polymerization in polyols or prepolymers having terminal isocyanate groups and their use in polyurethane formulations | 福漫有限责任两合公司 | 2024-01-12 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-110382512-B | Method for producing transition metal-isonitrile complex | 国立大学法人九州大学 | 2022-09-16 | — | — | CN | disclosed |
| US-8674128-B2 | Conductive organometallic framework | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120017668-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2382043-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | The Regents of the University of California (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010083418-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-22 | — | — | WO | disclosed |
| EP-1316819-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-20040026658-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1316819-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-4169030-A | PRODUCTION OF HYDROGEN FUEL BY SOLAR PHOTOLYSIS OF WATER | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120017668-A1 | CONDUCTIVE ORGANOMETALLIC FRAMEWORK | IDH2, DBF4, HCN4 | DHFR 2865/4885MEN1 991/4885KMT2A 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.