Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 5/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296181 | 1.00 | KMT2A (0.51) | KMT2AMEN1POLBMAPK1FLT3 | |
| SCHEMBL539219 | 0.86 | AXL (0.59) | KMT2AMEN1POLBFLT3PDGFRB | |
| SCHEMBL29952094 | 0.77 | CA12 (0.45) | KMT2AMEN1POLBMAPK1FLT3 | |
| SCHEMBL1621740 | 0.77 | CA12 (0.45) | KMT2AMEN1POLBMAPK1FLT3 | |
| SCHEMBL29956285 | 0.77 | DAO (0.51) | KMT2AMEN1FLT3HSD17B10HPGD | |
| SCHEMBL24671629 | 0.74 | KIF11 (0.49) | KMT2AMEN1CA2NPC1RAB9A | |
| SCHEMBL29954766 | 0.74 | KIF11 (0.49) | KMT2AMEN1CA2NPC1RAB9A | |
| SCHEMBL435522 | 0.74 | AXL (0.72) | KMT2AMEN1POLBMAPK1FLT3 | |
| SCHEMBL23932577 | 0.74 | CA2 (0.56) | KMT2AMEN1POLBMAPK1FLT3 | |
| SCHEMBL20370994 | 0.74 | ALOX5 (0.54) | KMT2AMEN1FLT3PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |